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Selective estrogen receptor modulators (SERMs) SERMs are a group of medications that function to disrupt binding of estrogen at estrogen receptors in the hypothalamus through competitive antagonism. In men, normal binding of estrogen at these receptors functions as an indirect negative feedback mechanism of endogenous testosterone production to downregulate GnRH and subsequently pituitary gonadotropin production. Therefore, SERMs function to block estrogen feedback thereby increasing GnRH and gonadotropin production and ultimately increasing ITT levels in men without evidence of primary hypogonadism, comprar stanozolol manipulado. CC exists as a racemic mixture of shorter acting enclomiphene (purely anti-estrogenic effects) and longer acting zuclomiphene (both estrogen agonist and antagonist effects) and exhibits a serum half-life of approximately 5 days. 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